Thorne Research | 5-Hydroxytryptophan 90 vegcaps
5-Hydroxytryptophan (5-HTP) is the intermediate metabolite produced when the body initiates the process of converting the essential amino acid L-tryptophan to serotonin. Serotonin levels in the body are associated with the regulation of sleep, mood, aggression, appetite, temperature, sexual behavior, and pain sensation.
Supplementing with 5-HTP to facilitate serotonin production is preferable to supplementing with L-tryptophan because, unlike L-tryptophan, 5-HTP cannot be shunted into niacin or protein production. Supplementation with 5-HTP bypasses the conversion of L-tryptophan into 5-HTP by the enzyme tryptophan hydroxylase, the rate-limiting step in the synthesis of serotonin and a step that can be inhibited by a number of factors, including stress, insulin resistance, increasing age, and deficiencies of vitamin C, folate, and iron.
5-HTP is well absorbed when taken orally, with about 70 percent ending up in the bloodstream.
Intestinal absorption of 5-HTP does not require the presence of a transport molecule and is not affected by the presence of other amino acids; therefore, it may be taken with meals without reducing its effectiveness. 5-HTP easily crosses the blood-brain barrier and effectively increases central nervous system (CNS) synthesis of serotonin.
5-HTP has been shown to have a beneficial impact on mood, discomfort associated with fatigue, sleep, and carbohydrate craving.* Numerous studies of individuals with negative mood status have shown significant positive response with 50-300 mg of 5-HTP daily.
To further facilitate serotonin production, Thorne Research's 5-HTP formula contains pyridoxal 5'-phosphate, the active form of vitamin B6 and the necessary cofactor for the conversion of 5-HTP to serotonin. 5-HTP is commercially produced by extraction from the seeds of the African plant, Griffonia simplicifolia.
Suggested Use: Take 1-2 capsules three times daily or as recommended by your health-care practitioner.
Serving Size: Two Capsules
Servings Per Container: 45
Two Capsules Contain:
Vitamin B6 (as Pyridoxal 5™-Phosphate) 6.8 mg
5-Hydroxytryptophan 100 mg
Other Ingredients: Microcrystalline Cellulose, Hypromellose (derived from cellulose) capsule, Leucine, Silicon Dioxide.
Tamper Evident: Use only if bottle is sealed.
WARNING: If pregnant, nursing, or trying to conceive, consult your health-care practitioner before using this product. Store tightly sealed in a cool, dry place.
Other DetailsThorne Research | 5-Hydroxytryptophan 90 vegcaps
5-HTP (5-Hydroxytryptophan or 5HTP)
Vitamin B-6 (pyridoxal 5' phosphate)
Cellulose, Hypromellose, Leucine, Microcrystalline cellulose, Silicon dioxide.